![]() Recanalization was the strongest predictor of good outcome. Recanalization ( P<0.0001 risk ratio, 2.7 95% confidence interval, 1.5–4.6) was the strongest predictor of outcome (adjusted for age and National Institutes of Health Stroke Scale score).Ĭonclusions-A low rate of acute recanalization was observed with IV rt-PA in proximal vessel occlusions identified by baseline CT angiogram. Onset to rt-PA time was comparable in patients with and without recanalization. By occlusion subtype, the rates of recanalization were: distal ICA (with or without ICA neck occlusion or stenotic disease) 1 of 24 (4.4%) M1-MCA (with or without ICA neck occlusion or stenotic disease) 21 of 65 (32.3%) M2-MCA 4 of 13 (30.8%) and basilar artery 1 of 25 (4%). Among the patients undergoing TCD (n=46) and cerebral angiogram (n=103), only 27 (21.25%) patients had acute recanalization. Of these, 216 patients had received IV rt-PA 127 patients underwent further imaging to assess recanalization. Results-Among 1341 patients in the CT angiogram database, 388 patients with proximal occlusion were identified. Modified Rankin Scale score ≤2 at 3 months was used as a good outcome. Rates of acute recanalization as observed on TCD/first run of angiogram and postendovascular therapy recanalization rates were noted. All patients with proximal vessel occlusions receiving IV rt-PA who were assessed for recanalization by TCD or angiogram (for acute endovascular treatment) were included for analysis. Materials and Methods-The CT angiogram database of the Calgary stroke program was reviewed for the period 2002 to 2009. We aimed to study acute recanalization rates of IV rt-PA in CT angiogram-proven proximal (internal carotid artery, M1 middle cerebral artery, M2-MCA, and basilar artery) occlusions and their effects on outcome. Customer Service and Ordering Informationīackground and Purpose-Acute rates of recanalization after intravenous (IV) recombinant tissue plasminogen activator (rt-PA) in proximal vessel occlusion have been estimated sparingly, typically using transcranial Doppler (TCD).Stroke: Vascular and Interventional Neurology.Journal of the American Heart Association (JAHA).Circ: Cardiovascular Quality & Outcomes. ![]() Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB).If you are not satisfied with the progress, you can click the Give Up button at the bottom left corner to quit the current game. Click the stock pile to deal a new card whenever necessary. If the reserve pile is used up, an empty tableau pile can be occupied by any card. When a tableau pile is empty, a card from the reserve pile will automatically move to fill the position. ![]() Cards on the tableau piles should be built down by alternating colors, wrapping from A to K if necessary. ![]() The cards can be arranged on the tableau piles before moving to the foundations. The foundations at the top right corner will be dealt 1 upturned card as the demon, while each of the 4 tableau piles underneath will also be dealt 1 upturned card. Then 1 upturned card will be dealt to the discard pile on the right of the stock pile, and 13 cards will be dealt to the reserve pile under the discard pile. When the game starts, all cards are downturned and placed on the stock pile at the top left corner. Cards in the foundations should also be built up by suit, wrapping from K to A if necessary. Yet it comes with a twist that the order of cards in the foundations must start with the number of the demon card dealt to the foundations, for example, if a 6 is dealt to the foundations, then each of the foundations must start with a 6. Play and see whether the demon card is a friend or a foe! The object of this game seems simple - to move all cards to 4 foundations.
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